University of Connecticut

Events Calendar

CCAM Seminar Series - Meier-Schellersheim

Thursday, February 26, 2015
4:00pm – 5:00pm

UConn Health
CGSB, 400 Farmington Ave., CCAM Conference Room, R1673

CCAM Seminar Series Guest: Martin Meier-Schellersheim Title: "Computational models that help us understand cellular signaling behavior" Host: Leslie Loew

Abstract: Faced with the complexity of living systems, biomedical research has traditionally focused on strongly confined questions that could be answered with experiments providing ‘yes-or-no’ answers, for example, blocking a component A will modify the behavior of another component B’. Driven by recent advances in experimental techniques that permit high-throughput profiling of biological samples or acquiring high-resolution images at the sub-cellular level, the ambition of researchers has become to understand the function of entire networks of interacting components underlying physiological regulatory processes. Fortunately, we are currently witnessing break-throughs in computational capabilities that parallel those seen in the experimental realm. Using examples from cellular signaling pathways and cell migration assays I will discuss how computational approaches allow us to test hypotheses that could not be explored without such support. I will extrapolate to suggest that realistic simulations will be driving elements of biomedical research in the not too far future.


Tiffany Gough,

Center for Cell Analysis and Modeling (primary)

Control Panel