University of Connecticut

Events Calendar

JAX-GM Seminar

Tuesday, May 10, 2016
1:00pm – 2:00pm

UConn Health
JAX-GM Auditorium

“Statistical Analysis of Massive Genetic and Genomic Data for Complex Diseases” Presented by: Xihong Lin, Ph.D., Henry Pickering Walcott Professor of Biostatistics Chair, Department of Biostatistics, Harvard School of Public Health JAX-GM Auditorium Host: Dr. Zhengqing Ouyang The human genome project in conjunction with the rapid advance of high throughput technology has transformed the landscape of health science research. The genetic and genomic era provides an unprecedented promise of understanding genetic underpinnings of complex diseases or traits, studying gene-environment interactions, predicting disease risk, and improving prevention and intervention, and advancing precision medicine. A large number of genome-wide association studies conducted in the last ten years have identified over 1,000 common genetic variants that are associated with many complex diseases and traits. Massive targeted, whole exome and whole genome sequencing data as well as different types of ‘omics data have become rapidly available in the last few years. These massive genetic and genomic data present many exciting opportunities as well as challenges in data analysis and result interpretation. They also call for more interdisciplinary knowledge and research, e.g., in statistics, machine learning, data curation, molecular biology, genetic epidemiology and clinical science. In this talk, I will discuss analysis strategies for some of these challenges, including rare variant analysis of whole-genome sequencing association studies; analysis of multiple phenotypes (pleiotropy), and integrative analysis of different types of genetic and genomic data.


Julie Yarmolovich –

UConn Health Master Calendar (primary), UConn Master Calendar

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